Plasmid-Encoded Tet B Tetracycline Resistance in Haemophilus parasuis

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Plasmid-encoded Tet B tetracycline resistance in Haemophilus parasuis.

The complete sequence of two plasmids, pHS-Tet (5.1 kb) and pHS-Rec (9.5 kb), isolated from Haemophilus parasuis strain HS1543 has been obtained. Plasmid pHS-Tet contains four open reading frames including a tet(B) tetracycline resistance gene which unusually did not have an associated tetR repressor gene. From a total of 45 H. parasuis isolates surveyed (15 international reference strains, 15 ...

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Sir, The Gram-negative bacterium Haemophilus parasuis is the causative agent of Glässer’s disease, which is characterized by various combinations of meningoencephalitis, polyserositis, polyarthritis and bacterial pneumonia, resulting in major economic losses to the swine industry worldwide. Florfenicol is used exclusively in veterinary medicine and was approved for the treatment of porcine resp...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 2005

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.49.5.1927-1931.2005